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Multiple sclerosis: Association of gelatinase B/matrix metalloproteinase-9 with risk and clinical course the disease.

Multiple sclerosis and related disorders - 1 Jan 2017

Valado Ana, Leitão Maria João, Martinho António, Pascoal Rui, Cerqueira João, Correia Inês, Batista Sónia, Sousa Lívia, Baldeiras Inês

Abstract excerpt

BACKGROUND: Multiple sclerosis (MS) is an autoimmune disease characterized by inflammation and axonal degeneration of the central nervous system and a leading cause of disability in young adults. The matrix metalloproteinases in general and specially gelatinase B/metalloproteinase-9 (MMP-9) plays a role in the pathogenesis of multiple sclerosis. OBJECTIVE: To investigate the presence of the MMP-9 -1562C/T...

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PMID: 28104261
DOI: 10.1016/j.msard.2016.12.003

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