Article
Functional polymorphism of the matrix metalloproteinase-9 (MMP-9) gene in schizophrenia.
Schizophrenia research - 1 Apr 2009
Rybakowski Janusz K, Skibinska Maria, Kapelski Pawel, Kaczmarek Leszek, Hauser Joanna
Abstract excerpt
Matrix metalloproteinase-9 (MMP-9) plays a role in many pathological conditions (e.g. cancer and heart disease). Recently, MMP-9 has been implicated in the activity of the prefrontal cortex and we therefore hypothesized that the MMP-9 gene may be associated with schizophrenia. We genotyped the functional -1562C/T polymorphism in a group of 442 schizophrenia patients and in 558 healthy control subjects. A...
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