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Clinical Factors Associated With Merkel Cell Polyomavirus Infection in Merkel Cell Carcinoma

18 Jun 2009

Abstract excerpt

BACKGROUND: Merkel cell carcinoma is a rare malignancy of the skin. Integration of Merkel cell polyomavirus (MCPyV) DNA to the tumor genome is frequent in these cancers. The clinical consequences of MCPyV infection are unknown. METHODS: We analyzed formalin-fixed paraffin-embedded Merkel cell carcinoma tissue samples from 114 of 207 patients diagnosed with Merkel cell carcinoma in Finland from 1979 to 2004 for...

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PMID: 19535775
DOI: 10.1093/jnci/djp139

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