Article
Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression.
BMC psychiatry - 12 Nov 2013
Culverhouse Robert C, Bowes Lucy, Breslau Naomi, Nurnberger John I, Burmeister Margit, Fergusson David M, Munafò Marcus, Saccone Nancy L, Bierut Laura J
Abstract excerpt
BACKGROUND: Debate is ongoing about what role, if any, variation in the serotonin transporter linked polymorphic region (5-HTTLPR) plays in depression. Some studies report an interaction between 5-HTTLPR variation and stressful life events affecting the risk for depression, others report a main effect of 5-HTTLPR variation on depression, while others find no evidence for either a main or interaction effect....
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