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Article

Endothelial nitric oxide synthase gene Glu298Asp polymorphism is associated with advanced stage endometriosis.

Human reproduction (Oxford, England) - 1 Oct 2009

Kim Hoon, Ku Seung Yup, Kim Sung Hoon, Lee Gyoung Hoon, Choi Young Min, Kim Jong Mee, Lee Taek Hoo, Moon Shin Yong

Abstract excerpt

BACKGROUND: Altered expression of endothelial nitric oxide synthase (eNOS) has been reported to be involved in the development of endometriosis. The genotypes of eNOS gene (NOS3) may be responsible for variation in its enzymatic activity as well as plasma concentration of nitric oxide. The Glu298Asp polymorphism of the NOS3 may modulate angiogenesis and influence individual susceptibility to endometriosis. This...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19531501
DOI: 10.1093/humrep/dep212

Genes

NOS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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