Article
Association of Nitric Oxide Synthase and Matrix Metalloprotease Single Nucleotide Polymorphisms with Preeclampsia and Its Complications.
PloS one - 1 Jan 2015
Leonardo Daniela P, Albuquerque Dulcinéia M, Lanaro Carolina, Baptista Letícia C, Cecatti José G, Surita Fernanda G, Parpinelli Mary A, Costa Fernando F, Franco-Penteado Carla F, Fertrin Kleber Y, Costa Maria Laura
Abstract excerpt
BACKGROUND: Preeclampsia is one of the leading causes of maternal and neonatal morbidity and mortality in the world, but its appearance is still unpredictable and its pathophysiology has not been entirely elucidated. Genetic studies have associated single nucleotide polymorphisms in genes encoding nitric oxide synthase and matrix metalloproteases with preeclampsia, but the results are largely inconclusive across...
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