Article
Association of nitric oxide synthase gene polymorphisms (-786T>C, 4a4b, 894G>T) with primary ovarian insufficiency in Korean women.
Maturitas - 1 Feb 2013
Rah HyungChul, Jeon Young Joo, Lee Woo Sik, Jung Yong Wook, Choi Dong Hee, Kwon Hwang, Kim Ji Hyang, Shin Ji Eun, Kim Nam Keun
Abstract excerpt
OBJECTIVES: The aim of our study was to investigate whether the endothelial nitric oxide synthase (eNOS) gene polymorphisms -786T>C, 4a4b, and 894G>T that affect nitric oxide (NO) generation confer a risk for primary ovarian insufficiency (POI) in Korean women. STUDY DESIGN: We genotyped 136 POI patients and 236 controls among Korean women for the three single nucleotide polymorphism sites with PCR-RFLP analysis....
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