Article
The effects of NOS3 Glu298Asp variant on colorectal cancer risk and progression in Turkish population.
Molecular biology reports - 1 Mar 2012
Arıkan Soykan, Cacina Canan, Guler Erkan, Çulcu Serdar, Tuna Gulay, Yaylım-Eraltan Ilhan
Abstract excerpt
Endothelial nitric oxide synthase (eNOS), coded by the gene NOS3, may play an important role in uncontrollable cellular growth in several cancer types. Our study was performed to test the association between Glu298Asp polymorphisms in the NOS3 gene and colorectal cancer risk and progression. In this study, NOS3 Glu298Asp polymorphism was genotyped in 84 patients with colorectal cancer and 99 healthy subjects...
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