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Gap junction communication regulates luminal-myoepithelial crosstalk and cell differentiation in a bilayered human mammary epithelial cell model

2025-09-16

Abstract excerpt

Interactions between luminal and myoepithelial cells are essential for proper mammary gland development and function. However, only a few in vitro models allow the study of these interactions and their modulation by extrinsic factors. We developed a layered co-culture system (LCS) that mimics the bilayered architecture of the human breast epithelium, enabling direct contact and bidirectional crosstalk between lum...

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Literature Corpus work
21c3617f-0a25-56a7-8bfe-b2ea3af5ed7e
DOI
10.1101/2025.09.10.675435
Open publication

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Gap junction communication regulates luminal-myoepithelial crosstalk and cell differentiation in a bilayered human mammary epithelial cell modelDOI 10.1101/2025.09.10.675435
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