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Article

Homozygosity and risk of childhood death due to invasive bacterial disease.

BMC medical genetics - 12 Jun 2009

Lyons Emily J, Amos William, Berkley James A, Mwangi Isaiah, Shafi Mohammed, Williams Thomas N, Newton Charles R, Peshu Norbert, Marsh Kevin, Scott J Anthony G, Hill Adrian V S

Abstract excerpt

BACKGROUND: Genetic heterozygosity is increasingly being shown to be a key predictor of fitness in natural populations, both through inbreeding depression, inbred individuals having low heterozygosity, and also through chance linkage between a marker and a gene under balancing selection. One important component of fitness that is often highlighted is resistance to parasites and other pathogens. However, the...

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Identifiers

PMID: 19523202
DOI: 10.1186/1471-2350-10-55
PMCID: PMC2714084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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