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Article

Consanguinity and susceptibility to infectious diseases in humans.

Biology letters - 23 Aug 2009

Lyons Emily J, Frodsham Angela J, Zhang Lyna, Hill Adrian V S, Amos William

Abstract excerpt

Studies of animal populations suggest that low genetic heterozygosity is an important risk factor for infection by a diverse range of pathogens, but relatively little research has looked to see whether similar patterns exist in humans. We have used microsatellite genome screen data for tuberculosis (TB), hepatitis and leprosy to test the hypothesis that inbreeding depression increases risk of infection. Our...

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Identifiers

PMID: 19324620
DOI: 10.1098/rsbl.2009.0133
PMCID: PMC2684220

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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