Article
SNPs in the FOXP3 gene region show no association with Juvenile Idiopathic Arthritis in a UK Caucasian population.
Rheumatology (Oxford, England) - 1 Aug 2007
Eastell T, Hinks A, Thomson W
Abstract excerpt
OBJECTIVE: A region on the short arm of the X-chromosome, Xp11, has previously been linked to childhood-onset polyarthritis. Mapping to the linked region is FOXP3, a transcription factor that regulates regulatory T cell (T(reg)) development and function. The objective of this study was to determi...
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