Article
No association between the functional cannabinoid receptor type 2 Q63R variants and inflammatory bowel disease in Turkish subjects.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology - 1 Dec 2014
Yonal Oya, Eren Fatih, Yılmaz Yusuf, Atuğ Özlen, Över Hülya Hamzaoğlu
Abstract excerpt
BACKGROUND/AIMS: The endocannabinoid system can exert beneficial effects on gastrointestinal inflammation, and cannabinoid receptor-2 (CB2) agonists may represent a new therapeutic approach in inflammatory bowel disease (IBD). A functional CB2 Q63R polymorphism (rs35761398) in the CNR2 gene has been shown to affect the immunomodulating properties of the CB2 receptor. We sought to investigate whether the...
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