Article
Müller cell production of insulin-like growth factor-binding proteins in vitro: modulation with phenotype and growth factor stimulation.
Investigative ophthalmology & visual science - 1 Dec 2004
King Jeffery L, Guidry Clyde
Abstract excerpt
PURPOSE: Müller cells are present in diabetic fibrocontractive ocular tissues and generate tractional forces in response to insulin-like growth factors. Recent studies indicate that diabetes-associated increases in vitreous insulin-like growth factor activity are, in part, attributable to changes in insulin-like growth factor binding proteins (IGFBPs). The objectives of this study were to evaluate Müller cells as...
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