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Article

Basement membrane-dependent modification of phenotype and gene expression in human retinal pigment epithelial ARPE-19 cells.

Investigative ophthalmology & visual science - 1 Aug 2004

Turowski Patric, Adamson Peter, Sathia Julie, Zhang Jin Jun, Moss Stephen E, Aylward G William, Hayes Matthew J, Kanuga Naheed, Greenwood John

Abstract excerpt

PURPOSE: To use porcine lens capsule (PLC) as basement membrane for ARPE-19 cells and to characterize its effects on cell differentiation and gene expression. METHODS: Postconfluent cultures of ARPE-19 cells were established on either porous polyester filters or PLC membranes and characterized by electron microscopy, immunocytochemistry, and transepithelial electrical resistance measurements. Metabolic activity...

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PMID: 15277505
DOI: 10.1167/iovs.03-0943

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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