Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Induction of an aging mRNA retinal pigment epithelial cell phenotype by matrix-containing advanced glycation end products in vitro.

Investigative ophthalmology & visual science - 1 Sept 2001

Honda S, Farboud B, Hjelmeland L M, Handa J T

Abstract excerpt

PURPOSE: To determine an extensive mRNA phenotype of the established RPE cell line ARPE-19 when grown on a matrix modified by advanced glycation end products (AGEs). METHODS: Growth Factor Reduced Matrigel (Collaborative Biomedical Products, Bedford, MA) was nonenzymatically glycated with glycolaldehyde. ARPE-19 cells were seeded on both AGE-Matrigel and Matrigel and grown to confluence, and serum was withdrawn...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basement Membrane
Share to Annexin A5

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blotting, Northern

Share to Blotting, Southern

Share to Eye Proteins

Share to Glycation End Products, Advanced

Share to Growth Substances

Share to Pigment Epithelium of Eye

Source

Identifiers

PMID: 11527959

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Induction of an aging mRNA retinal pigment epithelial cell phenotype by matrix-containing advanced glycation end products in vitro.PMID 11527959Read ↗

Advanced glycation endproduct-induced aging of the retinal pigment epithelium and choroid: A comprehensive transcriptional responseSemantic proximity Read ↗

Differential Protein Profiling of Primary versus Immortalized Human RPE Cells Identifies Expression Patterns Associated with Cytoskeletal Remodeling and Cell SurvivalSemantic proximity Read ↗

The expression of native and cultured RPE grown on different matricesSemantic proximity Read ↗

Age-related changes in the transcriptional profile of mouse RPE/choroidSemantic proximity Read ↗

Serum-deprivation response of ARPE-19 cells; expression patterns relevant to age-related macular degenerationSemantic proximity Read ↗

Serum-deprivation response of ARPE-19 cells; expression patterns relevant to age-related macular degenerationSemantic proximity Read ↗

Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells.Semantic proximity Read ↗

Parainflammation associated with advanced glycation endproduct stimulation of RPE in vitro: Implications for age-related degenerative diseases of the eyeSemantic proximity Read ↗

Basement membrane-dependent modification of phenotype and gene expression in human retinal pigment epithelial ARPE-19 cells.Semantic proximity Read ↗

Mouse retinal pigmented epithelial cell lines retain their phenotypic characteristics after transfection with human papilloma virus: a new tool to further the study of RPE biology.Semantic proximity Read ↗

Similarity of mRNA phenotypes of morphologically normal macular and peripheral retinal pigment epithelial cells in older human eyes.Semantic proximity Read ↗

Epithelial phenotype and the RPE: is the answer blowing in the Wnt?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.