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Article

Structural and functional analysis of a nuclear localization signal in SOCS1.

Molecular immunology - 1 Aug 2009

Koelsche Christian, Strebovsky Julia, Baetz Andrea, Dalpke Alexander H

Abstract excerpt

Suppressor of cytokine signaling 1 (SOCS1) belongs to a family of genes involved in inducible feedback inhibition of janus kinases (JAKs) and signal transducers and activators of transcription (STATs) signaling pathway. Recently, we were able to show that SOCS1 surprisingly translocates to the nucleus due to the presence of a functional nuclear localization signal (NLS). However, the precise nature of the NLS...

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Source

Identifiers

PMID: 19515423
DOI: 10.1016/j.molimm.2009.05.020

Genes

SOCS1
STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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