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Article

Identification of a nuclear localization signal in suppressor of cytokine signaling 1.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Dec 2008

Baetz Andrea, Koelsche Christian, Strebovsky Julia, Heeg Klaus, Dalpke Alexander H

Abstract excerpt

Suppressor of cytokine signaling (SOCS) proteins are inducible feedback inhibitors of janus kinase and signal transducer and activators of transcription signaling pathways. In addition, SOCS1 has been identified to regulate stability of nuclear NF-kappaB subunits. However, details about the regulation of the nuclear pool of SOCS1 are unknown. Using different experimental approaches, we observed that SOCS1 but no...

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Source

Identifiers

PMID: 18725457
DOI: 10.1096/fj.08-116079

Genes

SOCS1
SOCS3
STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification of a nuclear localization signal in suppressor of cytokine signaling 1.PMID 18725457Read ↗

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SOCS, SPRED, and NR4a: Negative regulators of cytokine signaling and transcription in immune toleranceSemantic proximity Read ↗

SOCS: suppressors of cytokine signalling.Semantic proximity Read ↗

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