Article
[Genomic study of susceptibility genes for common bone and joint diseases].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jun 2009
Ikegawa Shiro
Abstract excerpt
Common bone and joint diseases like osteoarthritis and lumbar disc disease are polygenic diseases caused by genetic and environment factors. We are challenging susceptibility genes for common bone and joint diseases using association study as a tool. By a combination of candidate-gene approach and whole-genome screen, we have succeeded in identification of five genes for osteoarthritis and for lumbar disc...
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