Article
[Genetic basis for skeletal disease. Genetic factors of osteoarthritis with particular reference to skeletal dysplasia].
Clinical calcium - 1 Aug 2010
Ikegawa Shiro
Abstract excerpt
Osteoarthritis (OA) is a degenerative disease of articular cartilage. Etiologically, it is classified as primary (idiopathic) and secondary forms. Primary OA is a polygenic disease based on genetic and environmental factors. Identification of its genetic factor, i.e., the susceptibility genes is rapidly in progress. Skeletal dysplasia, inherent failure of formation and/or development of the skeleton, is the...
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