Article
Evidence for balancing selection acting on KIR2DL4 genotypes in rhesus macaques of Indian origin.
Immunogenetics - 1 Jul 2009
Blokhuis Jeroen H, van der Wiel Marit K, Doxiadis Gaby G M, Bontrop Ronald E
Abstract excerpt
The interaction of killer-cell immunoglobulin-like receptors (KIR) and their respective major histocompatibility complex (MHC) ligands can alter the activation state of the natural killer (NK) cell. In both humans and rhesus macaques, particular types of non-classical MHC class I molecules are predominantly expressed on the trophoblast. In humans, human leukocyte antigen G has been demonstrated to act as a ligand...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
