Article
Prostate cancer (PCa) risk variants and risk of fatal PCa in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium.
European urology - 1 Jun 2014
Shui Irene M, Lindström Sara, Kibel Adam S, Berndt Sonja I, Campa Daniele, Gerke Travis, Penney Kathryn L, Albanes Demetrius, Berg Christine, Bueno-de-Mesquita H Bas, Chanock Stephen, Crawford E David, Diver W Ryan, Gapstur Susan M, Gaziano J Michael, Giles Graham G, Henderson Brian, Hoover Robert, Johansson Mattias, Le Marchand Loic, Ma Jing, Navarro Carmen, Overvad Kim, Schumacher Fredrick R, Severi Gianluca, Siddiq Afshan, Stampfer Meir, Stevens Victoria L, Travis Ruth C, Trichopoulos Dimitrios, Vineis Paolo, Mucci Lorelei A, Yeager Meredith, Giovannucci Edward, Kraft Peter
Abstract excerpt
BACKGROUND: Screening and diagnosis of prostate cancer (PCa) is hampered by an inability to predict who has the potential to develop fatal disease and who has indolent cancer. Studies have identified multiple genetic risk loci for PCa incidence, but it is unknown whether they could be used as biomarkers for PCa-specific mortality (PCSM). OBJECTIVE: To examine the association of 47 established PCa risk...
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