Article
The association of PLA2G2A single nucleotide polymorphisms with type IIa secretory phospholipase A2 level but not its activity in patients with stable coronary heart disease.
Gene - 10 Jun 2015
Shuvalova Yulia A, Khasanova Zukhra B, Kaminnaya Violetta I, Samoilova Elena V, Korotaeva Alexandra A, Rubanovich Alexander V, Kaminnyi Alexander I
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) of the secretory phospholipase A2 type IIa (sPLA-IIa) gene (PLA2G2A) affect sPLA2-IIa level and activity in patients with diabetes mellitus, acute coronary syndrome or recent cardiovascular surgical interventions. Our study examined the effects of PLA2G2A SNPs on sPLA2-IIa levels and activity in patients with stable CHD. METHODS AND RESULTS: The study included a...
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