Article
Germline variation of the melanocortin-1 receptor does not explain shared risk for melanoma and thyroid cancer.
Experimental dermatology - 1 Jun 2009
Bauer Jürgen, Weng Julie, Kebebew Electron, Soares Paula, Trovisco Vitor, Bastian Boris C
Abstract excerpt
BACKGROUND: Recently, germline variants of the melanocortin-1 receptor (MC1R) have been shown to be associated with an increased risk for BRAF mutant but not BRAF wild-type cutaneous melanoma. Similar to melanoma, BRAF mutations are also commonly found in papillary thyroid carcinomas. Furthermore, patients with melanoma have an increased risk for thyroid carcinoma and vice versa. METHODS: To determine whether...
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