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Article

Germline variation of the melanocortin-1 receptor does not explain shared risk for melanoma and thyroid cancer.

Experimental dermatology - 1 Jun 2009

Bauer Jürgen, Weng Julie, Kebebew Electron, Soares Paula, Trovisco Vitor, Bastian Boris C

Abstract excerpt

BACKGROUND: Recently, germline variants of the melanocortin-1 receptor (MC1R) have been shown to be associated with an increased risk for BRAF mutant but not BRAF wild-type cutaneous melanoma. Similar to melanoma, BRAF mutations are also commonly found in papillary thyroid carcinomas. Furthermore...

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Source

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Identifiers

PMID: 19493000
DOI: 10.1111/j.1600-0625.2008.00827.x
PMCID: PMC2862686

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19493000-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Germline variation of the melanocortin-1 receptor does not explain shared risk for melanoma and thyroid cancer.PMID 19493000Read ↗

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The MC1R r allele does not increase melanoma risk in MITF E318K carriers.Semantic proximity Read ↗

Population-based study of natural variation in the melanocortin-1 receptor gene and melanoma.Semantic proximity Read ↗

The association between MC1R genotype and BRAF mutation status in cutaneous melanoma: findings from an Australian population.Semantic proximity Read ↗

MC1R germline variants confer risk for BRAF-mutant melanoma.Semantic proximity Read ↗

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Influence of loss of function MC1R variants in genetic susceptibility of familial melanoma in Spain.Semantic proximity Read ↗

Distribution of MC1R variants among melanoma subtypes: p.R163Q is associated with lentigo maligna melanoma in a Mediterranean population.Semantic proximity Read ↗

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