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Article

Lack of somatic alterations of MC1R in primary melanoma.

Pigment cell & melanoma research - 1 Oct 2008

Kim R D, Curtin J A, Bastian Boris C

Abstract excerpt

Germline variation of the melanocortin 1 receptor gene (MC1R) is a risk factor for cutaneous melanoma. Recent studies have indicated that the risk is significantly higher for melanomas with somatic BRAF mutations, suggesting that MC1R variants may have a more specific role than their demonstrated effects on skin and hair pigmentation. To address the possibility that MC1R may act like a tumor suppressor gene by...

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Source

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Identifiers

PMID: 18761657
DOI: 10.1111/j.1755-148X.2008.00497.x
PMCID: PMC2825252

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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