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Endogenous cGMP regulates adult longevity via the insulin signaling pathway in <i>Caenorhabditis elegans</i>

31 May 2009

Abstract excerpt

G-proteins, including GPA-3, play an important role in regulating physiological responses in Caenorhabditis elegans. When confronted with an environmental stimulus such as dauer pheromone, or poor nutrients, C. elegans receives and integrates external signals through its nervous system (i.e. amphid neurons), which interprets and translates them into biological action. Here it is shown that a suppressed neuronal...

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PMID: 19489741
DOI: 10.1111/j.1474-9726.2009.00495.x

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