Article
[677T mutation of the MTHFR gene in adenomas and colorectal cancer in a population sample from the Northeastern Mexico. Preliminary results].
Revista de gastroenterologia de Mexico - 1 Jan 2000
Delgado-Enciso I, Martínez-Garza S G, Rojas-Martínez A, Ortiz-López R, Bosques-Padilla F, Calderón-Garcidueñas A L, Zárate-Gómez M, Barrera-Saldaña H A
Abstract excerpt
INTRODUCTION: Adequate intake of folates has been associated to low prevalence of colon cancer. Methylenetetrahydrofolate reductase enzyme (MTHFR) plays an important role in folate metabolism. The role of the 677 mutation at the MTHFR gene in the risk for colorectal cancer remains controversial. A recent report established that this mutation has a high prevalence in the healthy Mexican population. AIMS: To...
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