Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The 5-HTTLPR polymorphism and posttraumatic stress disorder: a meta-analysis.

Journal of traumatic stress - 1 Dec 2013

Gressier Florence, Calati Raffaella, Balestri Martina, Marsano Agnese, Alberti Siegfried, Antypa Niki, Serretti Alessandro

Abstract excerpt

Environmental and genetic factors contribute to the development of posttraumatic stress disorder (PTSD). Variation in the 5-HTTLPR polymorphism of the serotonin transporter gene has been hypothesized to affect risk for PTSD. With the aim of investigating this association, we conducted a meta-analysis to shed light on prior controversial results and increase statistical power to detect smaller effect sizes. PubMed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Gene Frequency

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to Serotonin Plasma Membrane Transport Proteins

Source

Identifiers

PMID: 24222274
DOI: 10.1002/jts.21855

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The 5-HTTLPR polymorphism and posttraumatic stress disorder: a meta-analysis.PMID 24222274Read ↗

Meta-analyses of the 5-HTTLPR polymorphisms and post-traumatic stress disorder.Semantic proximity Read ↗

Serotonin transporter gene (SLC6A4) promoter polymorphisms and the susceptibility to posttraumatic stress disorder in the general population.Semantic proximity Read ↗

Meta-analysis of the interaction between serotonin transporter promoter variant, stress, and posttraumatic stress disorder.Semantic proximity Read ↗

Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations.Semantic proximity Read ↗

Serotonin transporter 5-HTTLPR genotype moderates the effects of childhood adversity on posttraumatic stress disorder risk: a replication study.Semantic proximity Read ↗

Interaction of Val66Met Brain-Derived Neurotrophic Factor and 5-HTTLPR Serotonin Transporter Gene Polymorphisms with Lifetime Prevalence of Post-Traumatic Stress Disorder in Primary Care Patients.Semantic proximity Read ↗

Serotonin transporter 5-HTTLPR genotype is associated with intrusion and avoidance symptoms of DSM-5 posttraumatic stress disorder (PTSD) in Chinese earthquake survivors.Semantic proximity Read ↗

The Association between Post-Traumatic Stress Disorder, 5HTTLPR, and the Role of Ethnicity: A Meta-Analysis.Semantic proximity Read ↗

Serotonin polymorphisms and posttraumatic stress disorder in a trauma exposed African American population.Semantic proximity Read ↗

The relationship between combat-related posttraumatic stress disorder and the 5-HTTLPR/rs25531 polymorphism.Semantic proximity Read ↗

An examination of the association between 5-HTTLPR, combat exposure, and PTSD diagnosis among U.S. veterans.Semantic proximity Read ↗

Influence of the serotonin transporter promoter gene polymorphism on susceptibility to posttraumatic stress disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.