Article
Mutational spectrum of conserved regions of TP53 and PTEN genes in Kangri cancer (of the skin) in the Kashmiri population.
Mutation research - 31 May 2009
Hussain Ishraq, ul Rehman Shakeel, Afroze Dil, Zahoor Lubna, Abdullah Safiya, Hafiz Adil, Shah Zafar A, Iqbal Shabir, Shaffi Mohammad, Das B C, Siddiqi Mushtaq A
Abstract excerpt
Kangri cancer is a unique, thermally induced squamous cell carcinoma (SCC) of the skin that develops due to persistent use of a Kangri (a brazier) by the Kashmiri people to combat the cold temperature during winter. Unlike classical UV-induced SCC of the skin, Kangri cancer appears on the legs and abdomen. Its common features are erythematous patches, recurrence and metastasis. In the absence of any molecular...
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