Article
High frequency of p53 gene mutations in primary breast cancers in Japanese women, a low-incidence population.
British journal of cancer - 1 Apr 1996
Hartmann A, Blaszyk H, Saitoh S, Tsushima K, Tamura Y, Cunningham J M, McGovern R M, Schroeder J J, Sommer S S, Kovach J S
Abstract excerpt
The pattern of acquired mutations in the p53 tumour-suppressor gene is potentially useful for determining factors contributing to carcinogenesis in diverse populations differing in incidence and/or mortality from the disease. We previously reported differences in mutational patterns of the p53 gene in primary breast cancers from Midwest US Caucasian, African-American and Austrian women. Herein, we report 16...
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