Article
CCR5-delta 32 allele is associated with the risk of developing multiple sclerosis in the Iranian population.
Cellular and molecular neurobiology - 1 Dec 2009
Shahbazi Majid, Ebadi Hamid, Fathi Davood, Roshandel Danial, Mahamadhoseeni Mana, Rashidbaghan Azam, Mahammadi Narges, Mahammadi Mahammad Reza, Zamani Mahdi
Abstract excerpt
The 32-base pair deletion on the C-C chemokine receptor 5 gene (CCR5-delta 32) is known as a protective allele against immune system disorders. We have studied this variation in Iranian multiple sclerosis (MS) patients and healthy controls. DNA samples were prepared from the whole blood of 254 patients with MS and 380 healthy controls. We amplified the fragment including the CCR5-delta 32 polymorphism and...
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