Article
Influence of CCR5 delta32 polymorphism on multiple sclerosis susceptibility and disease course.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Apr 2004
Silversides J A, Heggarty S V, McDonnell G V, Hawkins S A, Graham C A
Abstract excerpt
The CCR5 chemokine receptor has been implicated in the pathogenesis of multiple sclerosis (MS). We carried out an allelic association study using a deletion polymorphism in the coding region of the CCR5 gene in 331 relapsing-remitting (RR) and secondary progressive (SP) MS patients, 108 primary progressive (PP) MS patients and 230 healthy controls. Of the 331 RR and SPMS patients, 172 were recruited from...
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