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Article

A two-stage case-control association study of PADI2 with schizophrenia.

Journal of human genetics - 1 Jul 2009

Watanabe Yuichiro, Nunokawa Ayako, Kaneko Naoshi, Arinami Tadao, Ujike Hiroshi, Inada Toshiya, Iwata Nakao, Kunugi Hiroshi, Itokawa Masanari, Otowa Takeshi, Ozaki Norio, Someya Toshiyuki

Abstract excerpt

Peptidylarginine deiminases (PADIs), five isoforms of which have been identified, catalyze the conversion of arginine residues to citrulline residues in proteins. Recent studies have revealed that abnormal activation of PADI2, the gene for which is expressed throughout the nervous system, is likely to be related to the pathogenesis of neuropsychiatric diseases with neurodegenerative processes, such as Alzheimer's...

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Source

Identifiers

PMID: 19478818
DOI: 10.1038/jhg.2009.52

Genes

PADI2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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