Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Two-stage case-control association study of polymorphisms in rheumatoid arthritis susceptibility genes with schizophrenia.

Journal of human genetics - 1 Jan 2009

Watanabe Yuichiro, Nunokawa Ayako, Kaneko Naoshi, Muratake Tatsuyuki, Arinami Tadao, Ujike Hiroshi, Inada Toshiya, Iwata Nakao, Kunugi Hiroshi, Itokawa Masanari, Otowa Takeshi, Ozaki Norio, Someya Toshiyuki

Abstract excerpt

There is strong evidence for a negative association between schizophrenia and rheumatoid arthritis (RA). However, the mechanism for this association is unknown. We hypothesize that these two diseases share susceptibility genes. Recently, extensive studies have identified some RA susceptibility genes, including NFKBIL1, SLC22A4, RUNX1, FCRL3 and PADI4, in the Japanese population. To assess whether polymorphisms in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Rheumatoid
Share to Hydrolases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Organic Cation Transport Proteins

Share to Protein-Arginine Deiminase Type 4

Share to Protein-Arginine Deiminases

Share to Schizophrenia

Share to Symporters

Source

Identifiers

PMID: 19158815
DOI: 10.1038/jhg.2008.4

Genes

PADI4
FCRL3
NFKBIL1
RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Two-stage case-control association study of polymorphisms in rheumatoid arthritis susceptibility genes with schizophrenia.PMID 19158815Read ↗

Schizophrenia and Rheumatoid Arthritis Genetic Scenery: Potential Non-HLA Genes Involved in Both Diseases Relationship.Semantic proximity Read ↗

A two-stage case-control association study of PADI2 with schizophrenia.Semantic proximity Read ↗

Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.Semantic proximity Read ↗

Association between NR4A2 genetic variation and schizophrenia: A comprehensive systematic review and meta-analysis.Semantic proximity Read ↗

The genetic basis for the inverse relationship between rheumatoid arthritis and schizophrenia.Semantic proximity Read ↗

Replication of reported genetic associations of PADI4, FCRL3, SLC22A4 and RUNX1 genes with rheumatoid arthritis: results of an independent Japanese population and evidence from meta-analysis of East Asian studies.Semantic proximity Read ↗

Pathway-based association analysis of two genome-wide screening data identifies rheumatoid arthritis-related pathways.Semantic proximity Read ↗

The relationship between schizophrenia and rheumatoid arthritis revisited: genetic and epidemiological analyses.Semantic proximity Read ↗

Genetic analysis of common variants in the HDAC2 gene with schizophrenia susceptibility in Han Chinese.Semantic proximity Read ↗

Replication and cross-phenotype study based upon schizophrenia GWASs data in the Japanese population: support for association of MHC region with psychosis.Semantic proximity Read ↗

Two-stage additional evidence support association of common variants in the HDAC3 with the increasing risk of schizophrenia susceptibility.Semantic proximity Read ↗

Variants of the RELA gene are associated with schizophrenia and their startle responses.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.