Article
Association analysis of a functional variant in ATXN2 with schizophrenia.
Neuroscience letters - 6 Mar 2014
Zhang Fuquan, Wang Guoqiang, Shugart Yin Yao, Xu Yong, Liu Chenxing, Wang Lifang, Lu Tianlan, Yan Hao, Ruan Yanyan, Cheng Zaohuo, Tian Lin, Jin Chunhui, Yuan Janmin, Wang Zhiqiang, Zhu Wei, Cao Leiming, Liu Yansong, Yue Weihua, Zhang Dai
Abstract excerpt
Schizophrenia (SZ) is a severe mental disorder characterized by multiple neurodevelopmental dysfunctions including a breakdown of thinking process and a deficit of typical emotional responses. Ataxin-2 (ATXN2) plays vital roles in cell proliferation and growth, and functional mutations of ATXN2 cause neurodegenerative phenotypes, including spinocerebellar ataxia type 2 (SCA2) and amyotrophic lateral sclerosis...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.