Article
Genetic analysis of heme oxygenase-1 (HO-1) in German Parkinson's disease patients.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jul 2009
Funke Claudia, Tomiuk Juergen, Riess Olaf, Berg Daniela, Soehn Anne S
Abstract excerpt
Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons and the presence of intracytoplasmic inclusions (Lewy bodies). Iron, which is elevated in the substantia nigra (SN) of PD patients, seems to be of pivotal importance, because of its capacity to enhance the amplification...
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