Article
Notch-Delta signaling induces a transition from mitotic cell cycle to endocycle in Drosophila follicle cells.
Development (Cambridge, England) - 1 Dec 2001
Deng W M, Althauser C, Ruohola-Baker H
Abstract excerpt
In many developmental processes, polyploid cells are generated by a variation of the normal cell cycle called the endocycle in which cells increase their genomic content without dividing. How the transition from the normal mitotic cycle to endocycle is regulated is poorly understood. We show that the transition from mitotic cycle to endocycle in the Drosophila follicle cell epithelium is regulated by the Notch...
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