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Article

Regulation of cell proliferation and patterning in Drosophila oogenesis by Hedgehog signaling.

Development (Cambridge, England) - 1 May 2000

Zhang Y, Kalderon D

Abstract excerpt

The localized expression of Hedgehog (Hh) at the extreme anterior of Drosophila ovarioles suggests that it might provide an asymmetric cue that patterns developing egg chambers along the anteroposterior axis. Ectopic or excessive Hh signaling disrupts egg chamber patterning dramatically through primary effects at two developmental stages. First, excess Hh signaling in somatic stem cells stimulates somatic cell...

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PMID: 10769240
DOI: 10.1242/dev.127.10.2165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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