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Article

Absence of activating mutations of CXCR4 in pituitary tumours.

Clinical endocrinology - 1 Feb 2010

Lee Yong-ho, Noh Tae Woong, Lee Mi Kyung, Jameson J Larry, Lee Eun Jig

Abstract excerpt

OBJECTIVE: Mutations of the gsp oncogene are responsible for 30-40% of GH-producing pituitary adenomas and 10% of nonfunctioning pituitary adenomas (NFPAs). However, the pathogenetic mechanism of the remaining pituitary tumours still remains to be identified. Recently, the interaction between the chemokine stromal cell-derived factor 1 and its receptor CXCR4 was found to play an important role in GH production...

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Share to CXCR4 gene
Share to Immunohistochemistry
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pituitary Neoplasms

Share to Polymerase Chain Reaction

Share to Receptors, CXCR4

Source

Identifiers

PMID: 19473177
DOI: 10.1111/j.1365-2265.2009.03629.x

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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