Article

Transcriptional Profiling of Pituitary Adenoma Stem Cells: Unveiling the Pivotal Role of CXCR4 in Tumorigenesis and Clinical Applications

2023-08-31

Abstract excerpt

<h4>Background: </h4> Growth hormone-secreting pituitary adenoma (GHPA) is characterized by excessive growth hormone production and leads to clinical manifestations like acromegaly. The molecular intricacies underpinning the tumorigenesis of this neoplasm remain largely elusive, with tumor stem cells postulated to play a significant role. Method Human pituitary adenoma stem cells (hPASCs) were extracted and cultur...

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Literature Corpus work: 42388164-c3ad-546b-9e1a-dca08e4f6c0e
DOI: 10.21203/rs.3.rs-3291865/v1

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