G-proteins and hormonal signalling in human pituitary tumors: genetic mutations and functional alterations.

doi:10.1006/frne.1993.1007

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Article

G-proteins and hormonal signalling in human pituitary tumors: genetic mutations and functional alterations.

Frontiers in neuroendocrinology - 1 Jul 1993

Spada A, Vallar L, Faglia G

Abstract excerpt

In the last few years, molecular studies on pituitary adenomas have yielded several lines of evidence supporting a primary pituitary origin for these tumors. In fact, analyses of x-chromosomal inactivation show that the great majority of pituitary tumors are monoclonal in origin, suggesting that...

Topics

Animals
GTP-Binding Proteins
Humans
Hypothalamus
Mutation
Neurotransmitter Agents
Pituitary Neoplasms
Signal Transduction

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