Article
[Development of multicolour real time PCR for detection of drug resistance mutation in hepatitis B virus].
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology - 1 Dec 2010
Chen Zhao-Jun, Zhang La-Hong, Zhu Ming-Li, Liu Xia, Pan Feng, Xu Li-Qun, Zhao Xiao-Fei, Lin Bing
Abstract excerpt
OBJECTIVE: To set up a rapid method for detection of drug resistance mutation in HBV, based on multicolour real time PCR. To detect the mutation of blood serum, which were collected from patients. METHOD: To establish two reaction systems, each reaction system contains four resistance loci. On the new multicolor real time PCR method, the sensitivity and specificity were analysed, and detecting the drug resistant...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.