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Article

A prospective study of XRCC1 (X-ray cross-complementing group 1) polymorphisms and breast cancer risk.

Breast cancer research : BCR - 1 Jan 2005

Patel Alpa V, Calle Eugenia E, Pavluck Alexandre L, Feigelson Heather Spencer, Thun Michael J, Rodriguez Carmen

Abstract excerpt

INTRODUCTION: The gene XRCC1 (X-ray repair cross-complementing group 1) encodes a protein involved in DNA base excision repair. Two non-synonymous polymorphisms in XRCC1 (Arg194Trp and Arg399Gln) have been shown to alter DNA repair capacity in some studies in vitro. However, results of previous a...

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Identifiers

PMID: 16457697
DOI: 10.1186/bcr1355
PMCID: PMC1410742

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16457697-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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A prospective study of XRCC1 (X-ray cross-complementing group 1) polymorphisms and breast cancer risk.PMID 16457697Read ↗

XRCC1 Arg399Gln, Arg194Trp and Arg280His polymorphisms in breast cancer risk: a meta-analysis.Semantic proximity Read ↗

A population-based case-control study of the Arg399Gln polymorphism in DNA repair gene XRCC1 and risk of breast cancer.Semantic proximity Read ↗

XRCC1 polymorphisms and cancer risk: a meta-analysis of 38 case-control studies.Semantic proximity Read ↗

DNA Repair Mechanism Gene, XRCC1A ( Arg194Trp) but not XRCC3 ( Thr241Met) Polymorphism Increased the Risk of Breast Cancer in Premenopausal Females: A Case-Control Study in Northeastern Region of India.Semantic proximity Read ↗

[Relationship between polymorphisms of X-ray repair cross-complementing group 1 gene Arg194Trp, Arg399Gln and susceptibility of breast cancer].Semantic proximity Read ↗

Association of DNA repair genes XRCC1 (Arg399Gln), (Arg194Trp) and XRCC3 (Thr241Met) polymorphisms with the risk of breast cancer: a case-control study in Egypt.Semantic proximity Read ↗

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Impact of XRCC1 genetic variants on its tissue expression and breast cancer risk: A case-control study.Semantic proximity Read ↗

DNA-repair genetic polymorphisms and breast cancer risk.Semantic proximity Read ↗

XRCC1 Arg399Gln polymorphism confers risk of breast cancer in American population: a meta-analysis of 10846 cases and 11723 controls.Semantic proximity Read ↗

X-ray repair cross-complementing group 1 (XRCC1) genetic polymorphisms and cervical cancer risk: a huge systematic review and meta-analysis.Semantic proximity Read ↗

Association of the Arg194Trp and the Arg399Gln polymorphisms of the XRCC1 gene with risk occurrence and the response to adjuvant therapy among Polish women with breast cancer.Semantic proximity Read ↗

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