Cancer stem cells in hepatocellular carcinoma: Recent progress and perspective

Abstract excerpt

Although the "cancer stem cell (CSC)" hypothesis was first proposed roughly 50 years ago, recent progress in stem cell biology and technologies has successfully achieved the identification of CSCs in a variety of cancers. CSCs are defined as a minor population which possesses a prominent ability to generate new tumors that faithfully reproduce the phenotype of original tumors in xenotransplant assays....

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