Article
The cancer stem cell paradigm: a new understanding of tumor development and treatment
28 Apr 2010
Abstract excerpt
IMPORTANCE OF THE FIELD: Cancer is the second leading cause of death in the United States, and therefore remains a central focus of modern medical research. Accumulating evidence supports a 'cancer stem cell' (CSC) model - where cancer growth and/or recurrence is driven by a small subset of tumor cells that exhibit properties similar to stem cells. This model may provide a conceptual framework for developing more...