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The Biology of Cancer Stem Cells and Its Clinical Implication in Hepatocellular Carcinoma

30 Jan 2012

Abstract excerpt

Hepatocellular carcinoma (HCC) is a highly malignant tumor with limited treatment options in its advanced state. The molecular mechanisms underlying HCC remain unclear because of the complexity of its multi-step development process. Cancer stem cells (CSCs) are defined as a small population of cells within a tumor that possess the capability for self-renewal and the generation of heterogeneous lineages of cancer...

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PMID: 22375168
DOI: 10.5009/gnl.2012.6.1.29

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