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Cancer Stem cells and their cellular origins in primary liver and biliary tract cancers

5 Feb 2016

Abstract excerpt

UNLABELLED: Liver and biliary tract cancers are highly aggressive, are heterogeneous in their phenotypic traits, and result in clinical outcomes that are difficult to manage. Cancers have subpopulations of cells termed "cancer stem cells" (CSCs) that share common intrinsic signaling pathways for self-renewal and differentiation with normal stem cells. These CSCs likely have the potential to evolve over time and...

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PMID: 26849406
DOI: 10.1002/hep.28485

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