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Article

Stem cells in hepatocarcinogenesis: evidence from genomic data.

Seminars in liver disease - 1 Feb 2010

Marquardt Jens U, Thorgeirsson Snorri S

Abstract excerpt

Increasing evidence suggests that many, perhaps all solid tumors contain a subset of cells that possess functional properties similar to the normal tissue stem cells, including self-renewal, unlimited proliferative capacity, and pluripotency. The hierarchical cancer model that places a cancer stem cell (CSC) population at the apex of tumor formation is based on this notion. The cancer stem cell hypothesis posits...

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Share to Carcinogenicity Tests
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Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20175031
DOI: 10.1055/s-0030-1247130
PMCID: PMC3492884

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