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Article

HBV induced HCC: major risk factors from genetic to molecular level.

BioMed research international - 1 Jan 2013

Ayub Ambreen, Ashfaq Usman Ali, Haque Asma

Abstract excerpt

Hepatocellular carcinoma (HCC) is a deadly and emerging disease leading to death in Asian countries. High hepatitis B virus (HBV) load and chronic hepatitis B (CHB) infection increase the risk of developing HCC. HBV is a DNA virus that can integrate DNA into host genome thereby increase the yield of transactivator protein HBxAg that may deregulate many pathways involving in metabolism of cells. Several monogenic...

Topics

Carcinoma, Hepatocellular
Genetic Predisposition to Disease
Hepatitis B
Hepatitis B virus
Humans
Liver Neoplasms
Prevalence
Risk Factors

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 23991421
DOI: 10.1155/2013/810461
PMCID: PMC3749539

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-23991421-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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