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Article

HBV induced HCC: major risk factors from genetic to molecular level.

BioMed research international - 1 Jan 2013

Ayub Ambreen, Ashfaq Usman Ali, Haque Asma

Abstract excerpt

Hepatocellular carcinoma (HCC) is a deadly and emerging disease leading to death in Asian countries. High hepatitis B virus (HBV) load and chronic hepatitis B (CHB) infection increase the risk of developing HCC. HBV is a DNA virus that can integrate DNA into host genome thereby increase the yield of transactivator protein HBxAg that may deregulate many pathways involving in metabolism of cells. Several monogenic...

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Identifiers

PMID: 23991421
DOI: 10.1155/2013/810461
PMCID: PMC3749539

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Source receipt: pubmed, retrieved 7 Sept 2026.

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