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Article

Elevated serotonin 1A binding in remitted major depressive disorder: evidence for a trait biological abnormality.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Sept 2009

Miller Jeffrey M, Brennan Kathleen G, Ogden Todd R, Oquendo Maria A, Sullivan Gregory M, Mann J John, Parsey Ramin V

Abstract excerpt

Several biological abnormalities in major depressive disorder (MDD) persist during episode remission, including altered serotonin neurotransmission, and may reflect underlying pathophysiology. We previously described elevated brain serotonin 1A (5-HT(1A)) receptor binding in antidepressant-naive (AN) subjects with MDD within a major depressive episode (MDE) compared with that in healthy controls using positron...

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Source

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Identifiers

PMID: 19458612
DOI: 10.1038/npp.2009.54
PMCID: PMC2760406

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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